eShop » Process Filtration » Air/Gas Filtration » Corevital™ APB 0.2 μm PVDF Sterilizing-Grade Bricap L Capsule Filter, for Gas Filtration

Corevital™ APB 0.2 μm PVDF Sterilizing-Grade Bricap L Capsule Filter, for Gas Filtration

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Part No. L02SSAPBBA1P
$163.00 USD
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Corevital™ APB 0.2 μm hydrophobic PVDF filters are designed for reliable sterile gas filtration in biopharmaceutical processes. With excellent air permeability and robust membrane integrity, Corevital™ APB filters are well suited for critical gas filtration applications, including fermenter vent filtration and sterile air supply systems.

Features

  • Hydrophobic Polyvinylidene Fluoride (PVDF) Membrane: 0.2 μm membrane, features high throughput and high retention rate. Low differential pressure.
  • Sterilizing -grade Filter: Bacterial Retention validated according to ASTM F838, each filter is integrity tested prior to release.
  • Linear Scale Up: Available in syringe filter for filterability study, small-scale capsule filter for process development, and large-scale capusle filter and filter cartridge for commercial GMP manufacturing.

Applications

  • Vent filter for fermentation, storage tanks
  • Sterile filtration for compressed air, oxygen, nitrogen
  • Single-use system application

Quality Standards

  • ISO 9001: 2015 Quality Management System
  • Manufactured for use in conformance with cGMP
  • Each product is integrity tested prior to release
  • Unique serial number for full traceability
  • COA/COQ provided with shipment
  • Validation documents are available upon request
Physical Properties Filter Format Bricap™ C Capsule Filter
Scale Pilot Scale
Filtration Area 0.16 m², 0.25 m², 0.375 m², 0.75 m², 1.5 m², 2.25 m²
Pore Size 0.2 μm
Pre-filter /
Bubble Point (per 0.75 m²) ≥0.11 MPa at 20 °C, 60% IPA 40% water, air
Materials Membrane Material Polyvinylidene Fluoride (PVDF)
Support Fleece Polypropylene (PP)
Housing Material Polypropylene (PP)
O-ring / Seal Silicone
Operating Conditions Max. Differential Pressure (Forward) 0.55 MPa at 25 °C, 0.1 MPa at 80 °C
Max. Differential Pressure (Reverse) 0.21 MPa at 25 °C
Regulatory Compliance Compliance USP <788> Particulate Matter
USP <87> Cytotoxicity
USP <88> Biological Reactivity
FDA Indirect Food Additives, 21 CFR 177-182
ADCF Materials
Bacterial Retention 10⁷ cfu/cm² Brevundimonas diminuta (ATCC 19146) according to ASTM F838
Bacterial Endotoxin Endotoxin Limit of WFI System<0.25 EU/mL with the Limulus Amebocyte Lysate (LAL), USP <85>
Non-Fiber Releasing The products meet the criteria as defined in 21 CFR 210.3(b)(6)
Sterility Sterilization Method Autoclavable: 25 cycles for 30 min @130°C (SIP not compatible)

Gamma Compatible: can be sterilized by gamma irradiation or be autoclaved 5 cycles for 60 min @126°C

Pre-sterilized: by gamma irradiation at 25–45 kGy

Pre-sterilized: by autoclaved packed in cleansteam bag
Package Pack Size Pack of 1
Packaging Individually packed in a double PE bag

 
How to choose the materials for gas filters?

Gas filters are generally made from hydrophobic materials, such as PTFE and PVDF.

Is gas filtration precision the same as liquid filtration precision?

Because the filtration mechanisms differ between gases and liquids, gas filtration generally removes smaller particulate contaminants, so gas filtration precision is relatively higher than that of liquid filtration.

How to prevent premature clogging of gas filters?

1. Select appropriate filter materials and pore sizes based on product compatibility and impurity profile.
2. Adding a pre-filtration step to remove large particulates and extend the service life of the final sterilizing-grade filter.
3. Design and control the process to prevent premature filter wetting.

How to perform integrity testing for gas filters?

For most gas filters, water intrusion can be used for integrity testing. For gas filters with smaller surface areas or low water intrusion flow rates, organic solvents may also be used for wetting to conduct bubble point or difffusion flow tests.

What are the advantages and benefits of Cobetter gas filters?

1. A variety of materials to meet specific process requirements are available.
2. Different filtration precision configurations, such as single-layer, double-layer, and multi-layer setups, can enhance filtration flux and extended service life.
3. Hydrophobic and oleophobic properties improve resistance to clogging.
4. Strong chemical compatibility and high-temperature resistance.