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single-use mixing bag
single-use mixing bag

Lifecube™ MP Single-use Mixing Bag Sterile by Gamma Irradiation

In stock
Part No. BMP50LT41Y1K
$380.00 USD
Volume
Design
Sensor Ports
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*Ships within 3 Weeks
*Customers are responsible for any import duties or taxes
*Read our Shipping Policy and Refund Policy
*Not for medical use

Cobetter Lifecube Single-use Mixing Bags offer no-clean, many specifications, pre-sterilization, easy to install and flexibility of use, etc. The Lifecube Single-use Mixing bags are made of multi-layer co-extrusion film, feature good physical and chemical properties and extremely low gas permeability. Lifecube Single-use Mixing bags are suitable for a wide range of mixing steps in upstream and downstream processes.

Features

  • Magnetic suction/magnetic suspension mixing, integrated/split system, compatible with other brands
  • Fast installation, well mixing run and easy setup
  • Double-layer packaging, sterilized by 25~45 kGy gamma irradiation
  • Many specifications, meeting a variety of preparation applications
  • Customized bag sizes, flexibly match different specifications of containers
  • Customized Tubings, connectors and filters
  • Sensors can be customized to allow on-line monitoring during the process
  • Hardware with audit trail and automatic management functions available

Applications

  • Buffer and culture medium preparation
  • Semi-finished products preparation
  • Batch mixing

Quality Assurance

  • ISO 9001:2015 quality management system
  • ISO Class 4.8/ ISO 7/ ISO 8 cleanroom production
  • 100% leak testing
  • ADCF raw materials, complies with FDA 21 CFR Part 177-182 (Indirect food additives)
  • Meet the requirement of current USP <87> Class VI, Biological Reactivity Test, In Vitro
  • Meet the criteria of the current USP <88> Class VI, Biological Reactivity Test In Vitro
  • Aqueous extraction contains < 0.25 EU/mL as determined by Limulus Amebocyte Lysate (LAL), USP <85>
  • Particulate matter in the product eluent meets the requirements in USP <788> for large volume parenterals
  • Verify gamma irradiation dose according to ISO 11137
Materials Mixing Type
 Cobetter Lifecube MP Single-use Mixing Bags
Material Cobetter Topene™ RB Film

Impeller

(MPM)

 Materials of Construction

Main part/ Welding pad/ Plug: HDPE

Bearing: PVDF+Silicone Nitride
Volume 20L - 3000L
Total Fluid Contact Area 716 cm²
Main Height* 8 cm
Speed** ≤ 300 rpm
Tubing and Port Inlet

50/100/200 L: 150cm 3/8" ID x 5/8" OD Lifemeta™ STT Pt-cured Silicone tubing + ECS Female Quick Connector with plug;

500~3000 L: 150cm 1/2" ID x 3/4" OD Lifemeta™ STT Pt-cured Silicone tubing + ECM Female Quick Connector with plug.
Outlet

50/100/200 L: 150cm 3/8" ID x 5/8" OD Lifemeta™ STT Pt-cured Silicone tubing + ECS Male Quick Connector with plug;

500/1000 L: 150cm 1/2" ID x 3/4" OD Lifemeta™ STT Pt-cured Silicone tubing + ECM Male Quick Connector with plug;

1500~3000 L: 300cm 1/2" ID x 3/4" OD Lifemeta™ STT Pt-cured Silicone tubing + ECM Male Quick Connector with plug.
Sampling 20cm 1/4" ID x 7/16" OD Lifemeta™ STT Pt-cured Silicone tubing + Needlefree Swabable Valve
Powder Port 4" TC (including silicone gasket, blind cap and tri-clamp)
Sterility Delivery Condition Sterile
Sterilization Method Gamma Irradiation at 25–45 kGy
Package Packaging Individually packaged in double PE bags
Pack Size 1 pc/pk

Note:

*Height from the welding plate to the top of the impeller; 

**For reference only. The mixing speed is different from bag specifications, stirring volumes, solutions and brand of mixers. Please confirm the mixing speed and efficiency according to the actual situation.

 

Configuration Options

*Contact us for other configuration options.
  • Cobetter_Lifecube_Single-use_System_RB_film_20250915 Download
What are the specifications of Cobetter single-use mixing bags? What is the minimum mixing volume?

Cobetter single-use mixing bags are available in 20L, 50L, 100L, 200L, 500L, 1000L, 1500L, 2000L.

Generally, the minimum mixing volume for mixing bags is 20% of the nominal volume of the bag, assuming complete mixing. However, if the aim is to achieve mixing effects, then a liquid level that reaches the height of the paddle blades is generally sufficient.

What are the applicable conditions for the use of single-use mixing bags?

Cobetter single-use mixing bags are used for liquid-liquid mixing, solid-liquid mixing, such as media preparation, buffer preparation, intermediate product preparation, mixing of liquid collections from different batches, and so on.

The recommended temperature range is usually 0-40°C, pH range is 2.5-11.

What is the maximum mixing volume for Cobetter single-use mixing bags?

The maximum mixing volume for single-use mixing bags is 110% of the nominal volume. However, due to gas entering during the liquid filling process, the actual volume may be slightly smaller. If the liquid level is close to the maximum filling volume, it is recommended to add a vent filter.

What ISO cleanroom classifications apply to the manufacturing of Cobetter single-use bags?

Cobetter operates one ISO Class 5 manufacturing line dedicated to the production of filling system–related products. In addition, Cobetter is equipped with eleven ISO Class 7 and ISO Class 8 production lines for the manufacture of single-use storage bags, mixing bags, and customized tubing assemblies.

What tests are typically performed on Cobetter single-use bags prior to release?

A Certificate of Quality is provided with each shipment, listing routine test items and applicable reference standards. These tests include bag integrity, endotoxin levels, sterility, and insoluble particulate matter, among others.

What is the installation process for single-use storage bags and mixing bags?

When customers receive the bags, they need to remove the two layers of outer packaging. The films are attached together.

First, position the bag right and stretch the drainage tube out of the drainage hole of the container. If there is a mixing paddle, align it with the magnetic head position, adjust the bag.

Then fill the liquid while adjusting the position and angle of the bag to fit the container. If it is a square container, the weld position of the bag is different, so it is necessary to confirm the top and bottom first, and then operate. If it is a round container, it is necessary to adjust the bag to ensure that it is vertically placed and the bag body is in contact with the wall of the drum.

All adjustments must be made as quickly as possible during the liquid filling process. After the liquid filling is completed, the bag is too heavy to adjust (do not pull the film, tube, etc.). If the final fit is poor, If the final fit is poor, it increases the risk of damage. (Paper instructions are included with the shipment.)

What is the difference between magnetic stirring and magnetic levitation stirring?

Magnetic stirring: MP/MG series, with sufficient power and strong shear force, good mixing effect, and a rotation speed of usually ≤250rpm;

Magnetic levitation stirring: ML/MK/MKP/MS series, with gentle stirring, low shear force, a rotation speed of 250rpm-1000rpm, zero friction, but high cost.

There is no absolute good or bad, and the choice should be made based on the application.

Can single-use products be irradiated again after expiration?

No, the validation test of single-use products is based on one-time irradiation, and the strength of the material and risks such as E&L have not been systematically validated for multiple irradiations.

Will a single-use system that has been irradiated have any impact on the product? Can irradiation residues be detected in the irradiated items?

No. The irradiation dose is validated to ensure sterilization effectiveness. Moreover, the irradiation process only involves energy absorption and does not involve direct contact with the radiation source. Therefore, there are no issues of irradiation residues in the disposable system.