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Virus Filtration

Virus Filtration
Overview

Cobetter Viruclear™ virus removal filter adopts an asymmetric continuous gradient polyethersulfone (PES) membrane, which greatly improves the fouling-holding space and has strong trap ability for large particle impurities such as protein aggregates and potential viruses. The Viruclear™ virus filters also achieve good process linear scale up, while implementing integrity testing by easy-to-operate diffusion flow method.

SEM of Virus Removal Membrane


Viruclear™ VF Plus Virus Removal Filters

Cobetter Viruclear™ VF Plus virus removal filter is performance-optimized PES membrane based on the first generation Viruclear™VF. Viruclear™ VF Plus virus removal filter is mainly aimed at the purification of biological agents such as recombinant proteins expressed in animal cells, monoclonal antibodies, ADCs, higher purity/stability bispecific antibodies, etc.

Viruclear™ VF Plus X Virus Removal Filters

Viruclear™ VF Plus X is a newly launched virus removal filter based on PES membrane. It has better adaptability to complex products and higher volume capacity at the expense of a certain water flux, especially suitable for biological products with high protein aggregates content and poor stability, such as bevacizumab, unstable bispecific antibodies and fusion proteins.

Viruclear™ RC Virus Removal Filters

In order to deal with products that are the difficult to filter, Cobetter has launched new Viruclear™RC virus removal filter. The natural and excellent hydrophilicity of regenerated cellulose membrane enables lower adsorption, higher protein recovery and better filtration performance in complex products containing hydrophobic proteins, polymers and many impurities. 

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