Viruclear VF(PES) Plus X Virus Removal Plastic-housing Cassette, Lab and FLow
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Viruclear VF Plus X as a newly launched virus removal filter based on PES membrane ,has further improved structural fouling capacity. It has better adaptability to complex products and higher mass or volume capacity at the expense of a certain water flux, especially suitable for biological products with high protein aggregates content and poor stability, such as bevacizumab, unstable bispecific antibodies and fusion proteins. Viruclear VF Plus X is a supplement and alternative to Viruclear VF Plus in the fields of recombinant protein and antibody applications, and can take care of both filtration applications for some biological enzymes and low concentration blood products.
Specifications
| Physical Properties | Membrane Brand | ViruClear VF Plus X |
| Format | Pilot and Production scale | |
| Membrane Material | Hydrophilic Modified PES (mPES) | |
| Shell | PVDF | |
| Accessories Material | Silicone, PP | |
| Effective Filtration Area |
Pilot scale: 0.017/0.07/0.22 m² Production scale: 0.50/1.50 m² |
|
| Application |
Pilot scale: ≤200L Production scale: >200L |
|
| Package | Pack Size | 1/pk |
Features
- Unique surface hydrophilic improvement of PES membrane , which gives high mass capacity and high yield of virus retentive membrane
- Asymmetric membrane structure, high porosity, and high flux
- Robust removal of parvovirus
- ≥ 4.0 log removal of model virus
- Robust retention maintained during process interruption
- Chemically stable
- Easy to install, use and test
Application
- Monoclonal antibody
- Bispecific antibody
- Fc-fusion protein
- Nanobody
- Recombinant Covid vaccine
- Small molecule recombinant proteins (<180 kD), etc.