Consieve 2 TFF Cassette RC Ultrafiltration Membrane Lab, 1/pk
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Consieve™ 2 UFC RC membrane cassettes employ epoxy resin encapsulation, significantly increases structural rigidity and compression resistance, ensuring dimensional stability of flow channels. The cassettes demonstrate excellent linear scalability from lab-scale development to production-scale manufacturing. With optimized flow path configurations and multiple channel options, users can select the most suitable flow structure based on application requirements to improve process economics.
The regenerated cellulose (RC) ultrafiltration membrane demonstrates strong hydrophilicity, low absorption, low extractables, and excellent organic solvent resistance, offering advantages such as high flux, strong antifouling capability, and ease of cleaning/regeneration.
The cassettes should be used with Cobetter Stainless Steel TFF Cassette Holder:
EFA 0.01m² or 0.02m² cassettes use with Ultrafiltration Cassette Holders (0.01m²)
EFA 0.02m² or 0.11m² cassettes use with Ultrafiltration Cassette Holders (0.11m²)
EFA 0.5m²or 2.5m²cassettes use with Ultrafiltration Cassette Holders (0.5m²)
Specifications
| Materials | Membrane material | Regenerated Cellulose (RC) |
| Screen | PP | |
| Gasket | Silicone | |
| Edge Sealant | Epoxy Resin | |
| Permeate Sealant | Silicone | |
| Operating Conditions | Max. Operating Temperature | 50°C |
| Max. Operating Pressure | 4.0 bar | |
| pH range | 2.0-13.0 | |
| Sterility | Delivery Condition |
Nonsterile |
| Package | Pack Size | 1 pcs |
| Packaging | Individually packed in PE bag |
Screen Difference
| Screen Type | Flow Resistance | Flow Rate (LMM@dp 15psi Water) | Applications |
| Tight Screen | High | 5~6 | Generates the strongest turbulence on the membrane surface. Tight Screen can achieve relatively high tangential flow velocity at a relatively low inlet flow rate, but has a high pressure drop (dp) and is easily clogged by particles. Tight screen cassettes are suitable for samples without particles, low viscosity, and low concentration. |
| Standard Coarse Screen | Medium | 8~11 | Generates moderate turbulence on the membrane surface, reducing clogging. Standard Coarse Screen requires a higher inlet flow rate to match the appropriate tangential flow velocity. The pressure drop (dp) is significantly lower compared to Tight Screens. Standard coarse screen cassettes are suitable for clarified samples with medium to high viscosity. |
| Suspended Screen | Low | ≥40 | Generates the weakest turbulence and low shear force on the surface, but still significantly reduces clogging. Theoretically, Suspended Screen requires a very high inlet flow rate. Due to its open screen structure, it can accommodate more particles (cells, cell debris) without clogging. Suspended screen cassettes are suitable for unclarified samples with high particle content or high viscosity, and samples that are sensitive to shear force. |
Features
- Extra-low protein binding
- Wide chemical compatibility
- Compatible with organic solutions
- High product yield
- No glue used, resulting in low extractables
- pH range: 2-13
Applications
- Concentration and desalting of proteins, peptides or nucleic acids
- Buffer exchange
- Fractionation and purification
- Sample preparation before chromatography
- Remove pyrogens from water, buffers, media solutions
- COBETTER_Consieve_Cassettes_and_Systems_20240927 Download
