ViruClear VF Plus Virus Removal Silicone Cassette
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Optimizing the membrane preparation process based on the first generation Viruclear VF, Cobetter has launched the optimized composite PES membrane virus removal filter Viruclear VF Plus.
The strength of the optimized membrane structure is better guaranteed, the protein filtration capacity is effectively increased, and it has better adaptability to relatively complex products. ViruclearVF Plus, as the PES membrane virus retentive product line promoted by Cobetter, is mainly aimed at the purification of biological agents such as recombinant proteins expressed in animal cells, monoclonal antibodies, ADCs, higher purity/stability bispecific antibodies, etc.
Specifications
Physical Properties | Membrane Brand | ViruClear® VF Plus |
Format | Pilot and Production scale | |
Membrane Material | Hydrophilic Modified PES (mPES) | |
Shell | Silicone | |
Accessories Material | PP | |
Effective Filtration Area |
Pilot scale: 0.018/0.08/0.26 m² Production scale: 0.50/1.50 m² |
|
Application |
Pilot scale: ≤200L Production scale: >200L |
|
Package | Pack Size | 1/pk |
Features
- Unique surface hydrophilic improvement of PES membrane , which gives high mass capacity and high yield of virus retentive membrane
- Asymmetric membrane structure, high porosity, and high flux
- Robust removal of parvovirus
- ≥ 4.0 log removal of model virus
- Robust retention maintained during process interruption
- Chemically stable
- Easy to install, use and test
Application
- Monoclonal antibody
- Bispecific antibody
- Fc-fusion protein
- Nanobody
- Recombinant Covid vaccine
- Small molecule recombinant proteins (<180 kD), etc.