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Viruclear™ PCS Virus Removal Prefilter Cassette, Depth Filter Media, Lab to Pilot and Production Scale

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Part No. VPDSDSN1P
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*Not for medical use

Viruclear™ PDS virus removal prefilter is made of fully synthetic fibers and silica, providing adsorption performance comparable to PDT while meeting the requirements of customers with strict restrictions on animal- and plant-derived components (non-cellulose/diatomaceous earth). It is an excellent choice combining strong adsorption capability and broad compatibility.

Application

  • Monoclonal Antibody
  • Bispecific Antibody (BsAb)
  • Antibody-Drug Conjugate (ADC)
  • Fusion Proteins
  • Nanobody
  • Recombinant Proteins

Quality Standards

  • ISO 9001: 2015 Quality Management System
  • Manufactured for use in conformance with cGMP
  • Each product is integrity tested prior to release
  • COA/COQ provided with shipment
  • Validation documents are available upon request
Physical Properties Filter Format Viruclear™ PDS Cassette
Scale Lab to Pilot and Production Scale
Filtration Area Syringe Filter - 4.5 cm²
M02 Cassette - 0.027 m²
M02 Cassette - 0.054 m²
M02 Cassette - 0.11 m²
M02 Cassette - 0.55 m²
M02 Cassette - 1.1 m²
Applications Typical Application Virus Prefiltration
Materials Membrane Material Silicon dioxide, Composite fiber, Nylon
Housing Material Glass Fiber Reinforced Polypropylene
Accessories Silicone
Connections Inlet /
Outlet /
Sterility Delivery Condition Non-sterile
Sterilization Method /
Package Pack Size Pack of 1
Packaging Individually packed in double PE bag
  • Viruclear_VF_Series_Virus_Removal_Filter_20260112 Download
  • Application_Note_Viruclear_Performance_Data_Case_Study_Selection_Guide Download
What materials are available for Cobetter virus removal filters?

Currently Cobetter virus removal filters are available in two membrane materials: PES (polyethersulfone) and RC (regenerated cellulose).

How should the membrane material of virus removal filters be selected for antibodies and recombinant proteins?

For most antibodies and recombinant proteins, PES membranes are the preferred choice. However, when protein concentrations are high, purity is low, or protein stability is poor, RC (regenerated cellulose) membranes should be considered.

What is the preferred virus removal filter membrane for blood products?

RC (regenerated cellulose) membrane is the preferred choice for blood products. However, for factor products with relatively low molecular weight and low concentration, PES membranes may also be considered.

What formats and sizes are available for Cobetter PES and RC virus removal filters?

Cobetter PES and RC virus removal filters are available in multiple formats and sizes. Both PES and RC membranes are offered as small-scale syringe filters for filterability studies and virus clearance (VC) validation.

The PES series is available in plastic-housed formats, with membrane areas ranging from 0.017 m² to 1.5 m².
The RC series is provided in flat-sheet cassette formats, with membrane areas ranging from 0.015 m² to 1.5 m².

What materials are available for Cobetter virus removal prefiltration products?

Cobetter virus prefiltration products are available in the following membrane materials:
Nylon (PNY)
Polyethersulfone (PCE)
Polyvinylidene fluoride (PVDF, SMDA)
Composite materials (PDT)
Synthetic materials (PDS)

Are Cobetter virus removal filter available in sterile packaging?

PES virus removal filters are supplied in non-sterile packaging, while RC virus removal filters can be provided in sterile packaging.

What are the advantages and benefits of Cobetter virus filters?

1. High throughput, high loading capacity, and strong fouling resistance.
2. Robust viral clearance performance.
3. 100% integrity-tested before release, with scientifically supported integrity testing protocols provided to customers.
4. Comprehensive range of sizes and flexible installation for ease of use.