eShop » Single-Use Media Bottle Assemblies » 3-port Modular Silicone Closure Assembly, 53B, for Bottles and Carboys Pack of 1

3-port Modular Silicone Closure Assembly, 53B, for Bottles and Carboys Pack of 1

In stock
Part No. CSHLRR153
$190.00 USD
Cap Size
Port
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*Not for medical use

Cobetter Molded Silicone Seal Cap is a leakproof closure system, ensures secure connection during filtration processes. It is designed for aseptic handling solutions for biotechnology and laboratory liquid transfer application. It combines the chemical resistance of a Polypropylene (PP) body with the flexibility and sealing properties of silicone tubing to create a reliable, multi-purpose port solution.

Cobetter Molded Silicone Seal Cap include a polypropylene cap, a platinum-cured silicone stopper inserts and tubing. They are available with various ports, tubing lengths and closure sizes.

Compatibility

  • Use with Thermo Fisher Nalgene, or other brand bottles and carboys with 53B closures.
  • Replacement of Nalgene Top Works Platinum-cured Silicone, Polypropylene, Closure 2135-5303

Quality Standards

  • ISO 9001: 2015 Quality Management System
  • Manufactured for use in conformance with cGMP
  • Each product is integrity tested prior to release
  • COA/COQ provided with shipment
  • Validation documents are available upon request
  • TSE/BSE certificate available
Physical Properties Product Name Modular Silicone Closure Assembly
Cap Size 53B
Cap Color White
Number of Port 3
Materials Cap Material Polypropylene (PP)
Tubing Material Pt-cured silicone
Molded Seal Material Pt-cured silicone
Ports Outer Tube 1/8” ID x 1, 1/4” ID x 2
Dip Tube 1/4” ID x 2
Regulatory Compliance Compliance USP <788> Particulate Matter
USP <87> Cytotoxicity
USP <88> Biological Reactivity
FDA Indirect Food Additives, 21 CFR 177-182
ADCF Materials
Bacterial Endotoxin Endotoxin Limit of WFI System<0.25 EU/mL with the Limulus Amebocyte Lysate (LAL), USP <85>
Sterility Delivery Condition Non-sterile
Sterilization Method Can be sterilized by gamma Irradiation at 25-45 kGy

or Can be autoclaved for 30 min at 121°C
Package Pack Size Pack of 1
Packaging Individually packed in double PE bag

 
  • Cobetter_Lifecube_SSB_Single-use_Bottles_Catalog Download
Cobetter single-use bottles are available in PETG and PC materials. How to select the material?

PETG bottle has a relatively narrow temperature tolerance range and can be used within -40 to 60°C, while PC bottle offers a wider temperature tolerance range, suitable for -80 to 121°C. Customers can choose the appropriate material based on their application needs (e.g., sterilization method, chemical compatibility, light transmittance).

What are the applications of Cobetter single-use media bottle?

Cobetter Lifecube SSB single-use bottles are widely used in bio-pharmaceutical industry due to the sterility, convenience and low risk of cross-contamination. It can be used in many processes such as the storage and transmission of culture media and buffers, temporary storage of intermediate products, aseptic sampling and drugs freeze-thaw. PETG bottles are more suitable for the storage of culture media, buffers and other products, while PC bottles are more appropriate for the low-temperature storage of vaccines, antibodies and other products.

What are the available capacities for Cobetter single-use media bottles?

1. PETG bottles: 30/60/125/250/500mL and 1L

2. PC bottles: 125/250/500mL and 1L/2L

How are Cobetter single-use media bottles packaged?

Sterilized using double-layer packaging before being packed into cartons for transport.

What is the sterilization method for Cobetter single-use media bottles?

PETG bottles can only be sterilized by 25-45 kGy gamma irradiation and is not resistant to autoclaving. PC bottles can be sterilized by 25-45 kGy gamma irradiation or by autoclaving at 121℃.

* For autoclaving sterilization, fully loosen the cap to prevent deformation or leakage caused by differential thermal contraction between the cap and bottle body.