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BriScale™ VTC Disposable Vacuum Filter Unit PES Membrane Sterile

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Part No. VTC150MLEBSP
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*Not for medical use

Cobetter BriScale™ Vacuum Filtration Units are sterile by gamma irradiation and individually packaged, ready to use. Available in a wide range of configurations, these filtration units feature high flow rates, low protein binding, low extractables, and excellent chemical compatibility. They are well suited for laboratory applications including sterilizing filtration, particulate removal, sample clarification, and microbiological testing.

Features

  • Integrated welded funnel and connector design for leak-free performance
  • Large filtration area for faster processing
  • Lightweight design with a wide-mouth receiver bottle and low center of gravity for easy handling
  • High flow rate, high throughput, and low protein adsorption

Membrane Seletion Guide

Polyethersulfone (PES)

  • High flow rate, high flux, and low protein binding
  • Ideal for sterilizing filtration of most cell culture media and tissue culture media
  • Delivers excellent filtration performance and productivity

Hydrophilic Polyvinylidene Fluoride (PVDF)

  • Low protein binding for high product recovery
  • Suitable for the filtration of proteins, biological samples, and other valuable biomolecules

Nylon

  • Excellent mechanical strength and broad chemical compatibility
  • Resistant to dilute acids and compatible with many organic solvents
  • Well suited for organic solvent filtration and general laboratory applications

Mixed Cellulose Ester (MCE)

  • High porosity enables fast filtration rates
  • Excellent microbial retention performance
  • Ideal for the filtration of aqueous solutions and microbiological applications
Physical Properties Intended Use for Research Use Only
Filter Format BriScale™ Vacuum Filter Unit
Filtration Area 150 mL/250 mL: EFA - 41.8 cm² (φ73mm)

500 mL/1000 mL: EFA - 63.6 cm² (φ90mm)
Pore Size 0.1 /0.2 /0.45 /0.8 /1.0 μm
Wettability Hydrophilic
Materials Membrane Material Polyethersulfone (PES)
Funnel/ Lid/Receiver Bottle GPPS
Vacuum Tubing Barb/Bottle Cap High-Density Polyethylene (HDPE)
Funnel-to-Bottle Connector HIPS
Biocompatibility Compliance USP <87> In Vitro Biological Reactivity Test

USP <88> Biological Reactivity Test for Class VI plastics
Sterility Delivery Condition Sterile
Sterilization Method Gamma irradiation
Package Pack Size 150 /250 mL: Pack of 48

500 /1000 mL: Pack of 16
Packaging Individually packed in double PE bag
  • Cobetter_Laboratory_Consumables__Catalog__20260509 Download
What materials and specifications are available for Cobetter disposable vacuum filters?

Available materials: PES/PVDF/Nylon/MCE.

Specifications:
150mL：EFA 19.6 cm²
250mL：EFA 19.6 cm²
500mL：EFA 38.5 cm²
1000mL：EFA 63.6 cm²

What are the main applications of PES vacuum filter?

PES vacuum filters can be used for aqueous laboratory sample filtration, including buffers, culture media, cell harvest fluids, clarified E. coli lysates after centrifugation, and sterile filtration of proteins, among others.

Besides considering the chemical compatibility of the membrane, which other parts come into contact with the fluid and need to be evaluated for chemical compatibility?

The parts of a vacuum filter that come into contact with the fluid include:

Filter body: made of GPPS

Blue connector: made of PE (the liquid flows through this area and is in brief contact)

Common aqueous solutions are generally well compatible with these materials. If the fluid contains organic components, compatibility should be confirmed in advance. You may also consult Cobetter technical experts for verification.

Can Cobetter diposable vacuum filters be used in the aseptic operation room?

Cobetter vacuum filter cups can be used in the aseptic operation rooms. They are pre-sterile and packaged in double-layer bags. After entering the buffer area, the outer packaging can be removed, and the inner packaging can be brought into the aseptic operation room for unsealing and use.

Can the receiver bottle be stored directly in a freezer?

The receiver bottles can be stored and used briefly at low temperatures down to –70 °C, but long-term storage at this temperature is not recommended.

What filtration method is used for vacuum filters, and what are the recommended operating conditions?

Vacuum filters use negative-pressure (vacuum) filtration, typically paired with a vacuum pump.
The recommended operating pressure is –0.4 bar to –0.6 bar.
The connectors are compatible with tubing ID 1/2" (6.4 mm) to 3/8" (9.6 mm).

Can vacuum filter be reused?

Not recommended for reuse.
Cobetter vacuum filters are pre-sterilized by gamma irradiation and cannot be autoclaved, so they cannot be re-sterilized or reused.